PATH Malaria Vaccine Initiative, a charity supported by the Bill & Melinda Gates Foundation, in Seattle, is collaborating with the British drug maker GlaxoSmithKline PLC as well as clinics and research centers in Africa to develop a malaria vaccine, BusinessWeek reports.

Researchers seeking to create the world’s first malaria vaccine plan to start a medical trial next month involving 16,000 children, which could be the largest such trial ever conducted on children in Africa.